Foretinib, ≥98%

Catalog No. 873513

General Information

Synonyms	GSK1363089, EXEL-2880
CAS No.	849217-64-7
M.F.	C₃₄H₃₄F₂N₄O₆
M.W.	632.65

Technical Data

Appearance	White to off-white solid
Assay	≥98%
Solubility	DMSO
Storage	-20℃
Description	Foretinib (GSK1363089, XL880) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR.

Reference

Wang Q, et al. Cancer Lett. 2013 Jun 27. pii: S0304-3835(13)00472-2
Shah MA, et al. PLoS One. 2013;8(3):e54014
Choueiri TK, et al. J Clin Oncol. 2013 Jan 10;31(2):181-6
Zhang Z, et al. Nat Genet. 2012 Jul 1;44(8):852-60
Tiedt R, et al. Cancer Res. 2011 Aug 1;71(15):5255-64

Size	Price	Quantity	Favorites
5 mg	USD90
10 mg	USD170
50 mg	USD595

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

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Foretinib, ≥98%

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