Procarbazine hydrochloride, ≥99%

Catalog No. 087577

General Information

Synonyms	Mutulane, Natulan
CAS No.	366-70-1
M.F.	C₁₂H₁₉N₃O·HCl
M.W.	257.76
EC No.	206-678-6
MDL No.	MFCD00072082

Technical Data

Appearance	White crystal
Assay	≥99%
Solubility	DMSO, Methanol, Water
Storage	Protected from light
Description	Procarbazine is an antineoplastic alkylating agent widely used in cancer chemotherapy in combination with other compounds. It has multiple mechanisms of action. Procarbazine inhibits protein, RNA and DNA synthesis in addition to being an alkylating agent.

Safety Data

Symbol	GHS08 GHS07
Hazard Statements	H302-H341-H350-H360
Precautionary Statements	P201-P281-P308 + P313
Hazard Symbols	T
Risk Statements	R45-61-22-68
Safety Statements	S53-36/37-45
WGK Germany	3

Reference

Brada M, Stenning S, Gabe R, Thompson LC, Levy D, Rampling R, Erridge S, Saran F, et al. J. Clin. Oncol. 30, 4601-8, (2010)
Goerne R, Bogdahn U, Hau P. Curr. Med. Chem. 14, 1376-87, (2008)