Ivermectin, ≥98%

Catalog No. 232615

General Information

Synonyms	22,23-Dihydroavermectin B1, MK-933
CAS No.	70288-86-7
M.F.	C₄₈H₇₄O₁₄
M.W.	875.09
MDL No.	MFCD00869511
PubChem Substance ID	24278497

Technical Data

Appearance	White or yellowish-white crystalline powder
Assay	98% HPLC ((Bla+Blb); Bla ≥90% HPLC
Solubility	Chloroform, Methanol, Water
Storage	Cool & Dry
Description	Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor; also modulates glutamate-GABA-activated chloride channels.

Safety Data

Symbol	GHS08 GHS06
Hazard Statements	H300-H360
Precautionary Statements	P201-P264-P301 + P310-P308 + P313
Hazard Symbols	T+
Risk Statements	R61-28
Safety Statements	S53-28-36/37-45
WGK Germany	3

Reference

Adelsberger, H., et al. Eur. J. Pharmacol. 394, 163-170, (2000) Martin, R.J., et al. Int. J. Parasitol. 28, 849-862, (1998)
Krause, R.M., et al. Mol. Pharmacol. 53, 283-294, (1998)
Adelsberger, H., et al. Neurosci. Lett. 230, 183-186, (1997)
Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995)
Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988)