Melphalan, ≥98%

Catalog No. 061438

General Information

Synonyms	4-[Bis(2-chloroethyl)amino]-L-phenylalanine, L-PAM, L-Phenylalanine mustard
CAS No.	148-82-3
M.F.	C₁₃H₁₈Cl₂N₂O₂
M.W.	305.20
Beilstein No.	2816456
EC No.	205-726-3
MDL No.	MFCD00057717
PubChem Substance ID	24278538

Technical Data

Appearance	White to almost white powder
Assay	≥98%
Solubility	Soluble in methanol (< 3 mg/ml), and DMSO (< 3 mg/ml).
Storage	Protected from light
Description	Melphalan is a cytotoxic drug used to treat multiple myeloma. Phenylamine derivative of mechorethamine.

Safety Data

Symbol	GHS08 GHS06
Hazard Statements	H300-H310-H330-H350-H361
Precautionary Statements	P201-P260-P264-P280-P284-P302 + P350
Hazard Symbols	T+
Risk Statements	R45-46-63-26/27/28
Safety Statements	S53-22-36/37/39-45
UN No.	2811
Hazard Class	6.1
Packing Group	II
WGK Germany	3
RTECS	AY3675000

Reference

1. Ross, W.C.J., et al., Biochem. Pharmacol., 13, 969 (1964)
2. Donelli, M.G., et al., J. Pharm. Pharmacol., 18, 760 (1966)
3. Furner, R.L., et al., Cancer Treat. Rep., 64, 559 (1980)