Ivabradine hydrochloride, ≥99%

Catalog No. 273321

General Information

CAS No.	148849-67-6
M.F.	C27H36N2O5·HCl
M.W.	505.05
MDL No.	MFCD00929899

Technical Data

Appearance	White powder
Assay	≥99% HPLC
Solubility	DMSO, Methanol
Storage	2-8℃
Description	Ivabradine hydrochloride is an open channel blocker of neuronal I(h) and related cardiac I(f) channels. It has antianginal activity. It lowers heart rate and reduces myocardial oxygen demand.

Safety Data

Symbol	GHS09
Hazard Statements	H400
Precautionary Statements	P273
Hazard Symbols	N
Risk Statements	R50/53
Safety Statements	S60-61
WGK Germany	3

Reference

Lodhi M, et al. Int J Pharm Investig. 3(1):47-53, (2013)
Fang, Y., et al. J. Cardiovasc. Pharmacol. 59, 260-267, (2012)
Kroller-Schon, S., et al. Basic Res. Cardiol. 106, 1147-1158, (2011)
DiFrancesco, D., et al. Drugs, 64, 1757 (2004)
Borer, J.S., et al. Circulation, 107, 817 (2003)