Cyclosporin A, ≥98%

Catalog No. 181102

General Information

Synonyms	CsA, Ciclosporin A, Cyclosporine
CAS No.	59865-13-3
M.F.	C₆₂H₁₁₁N₁₁O₁₂
M.W.	1202.61
Beilstein No.	3647785
MDL No.	MFCD00274558

Technical Data

Assay	≥98% HPLC
Solubility	DMSO, Ethanol
Storage	-20℃
Description	Cyclosporin A is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. It inhibits phosphatase activity of calcineurin. It also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).

Reference

Kraeuter M, et al. Drug Des Devel Ther. 2013 Nov 28;7:1421-6
Guaguère E, et al. Vet Dermatol. 2004 Apr;15(2):61-74
Ho S, et al. Clin Immunol Immunopathol. 1996 Sep;80(3 Pt 2):S40-5
Liu J, et al. Cell. 1991 Aug 23;66(4):807-15

Size	Price	Quantity	Favorites
5 g	USD95
25 g	USD238
100 g	USD476

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Cyclosporin A, ≥98%

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