Gemcitabine hydrochloride, ≥99%

Catalog No. 177147

General Information

Synonyms	2′-Deoxy-2′,2′-difluorocytidine; dFdC, Gemzar (Lilly), LY-188011, dFdC, dFdCyd
CAS No.	122111-03-9
M.F.	C₉H₁₁F₂N₃O₄ · HCl
M.W.	299.66
MDL No.	MFCD01735988

Technical Data

Appearance	White crystalline powder
Specific Rotation (°)	+43°~+50°
Assay	≥99% HPLC
Solubility	Soluble in Water, Acetone and DMSO
Storage	Room temperature
Description	Gemcitabine hydrochloride is an antineoplastic.

Safety Data

Symbol	GHS08
Hazard Statements	H360
Precautionary Statements	P201-P308 + P313
Hazard Symbols	Xn
Risk Statements	R63-62
Safety Statements	S53-36/37
WGK Germany	3

Reference

Hertel et al (1990) Evaluation of the antitumor activity of Gemcitabine (2',2'-Difluoro-2'-deoxycytidine). Cancer Res. 50 4417. PMID: 2364394.

Heinemann et al (1995) Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism. Semin.Oncol. 22 (Suppl. 11) 11. PMID: 7481839.

Plunkett et al (1995) Preclinical characteristics of gemcitabine. Anticancer Drugs 6 (Suppl. 6) 7. PMID: 8718419.