Tiotropium bromide, ≥99%

Catalog No. 711578

General Information

Synonyms	(1α,2β,4β,5α,7β)-7-[(2-Hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
CAS No.	136310-93-5
M.F.	C₁₉H₂₂BrNO₄S₂
M.W.	472.42

Technical Data

Appearance	White or almost white powder
Melting Point (°C)	217-218℃
Specific Rotation (°)	-0.5°~+0.5°
Assay	≥99%
Solubility	Soluble in DMSO and Methanol
Storage	Protected from light
Description	Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation.

Reference

Haddad, E.-B., et al.: Mol. Pharmacol., 45, 899 (1994)

Donohue, J. F., et al.: Chest, 122, 47 (2002)

Profita, M., et al.: Allergy, 60, 1361 (2005)

Dusser, D., et al.: Eur. Respir. J., 27, 547 (2006)

Size	Price	Quantity	Favorites
5 mg	USD92
50 mg	USD552

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

> Certificate of Analysis

Inquire