LANCRIX

Triptolide, ≥98%

Catalog No. 557482

Identification
SynonymsNSC 163062; PG 490
CAS No.38748-32-2
M.F.

C20H24O6

M.W.360.40
MDL No.MFCD00210565
PubChem Substance ID24900156
Botanical Source Tripterygium wilfordii
Technical Data
AppearanceWhite powder
Melting Point (°C)226-227˚C
Purity≥98% HPLC
SolubilitySolube in Methanol, Ethyl acetate, Chloroform, DMSO, etc.
Storage2-8℃, protected from light
ApplicationInhibits cytokine-induced gene expression via inhibition of NF-κB transcriptional activity. Induces apoptosis in tumor cells by blocking TNF-α mediated c-IAP2 and c-IAP1 (members of the inhibitor of apoptosis family) induction. Immunosuppressive with anti-inflammatory and antitumor activity.
Safety Data
WGK Germany3
RTECSYK7751000
Reference

Hikim, S., et al.: J. Androl., 21, 431 (2000)

Chang, W.-T., et al.: J. Biol. Chem., 276, 222 (2001)

Kiviharju, T.M., et al.: Clin. Cancer Res., 8, 2666 (2002)

Leuenroth, S.J., et al.: Chem. Biol., 12, 1259 (2005)

Availability: Ships in 1-3 days

For research use only.

Inquire

(*Required Field)
*Name
*Organization Name
*Country
*Email Address
Phone
Subject 557482, Triptolide, ≥98%, 38748-32-2
*Message
*Code If it’s not clear, please click on the picture to change one.