LANCRIX

Cabozantinib malate, ≥99%

Catalog No. 405876

Identification
SynonymsXL184
CAS No.1140909-48-3
M.F.

C28H24FN3O5·C4H6O5

M.W.635.59
Technical Data
Assay≥99% HPLC
SolubilityDMSO
Storage-20℃
ApplicationCabozantinib is a potent VEGFR2 inhibitor. It also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL.
Safety Data
Reference

Smith DC, et al. J Clin Oncol. 2013 Feb 1;31(4):412-9
Viola D, et al. Future Oncol. 2013 Aug;9(8):1083-92
Kurzrock R, et al. J Clin Oncol. 2011 Jul 1;29(19):2660-6
Yakes FM, et al. Mol Cancer Ther. 2011 Dec;10(12):2298-308

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