EPZ5676, ≥98%
Catalog No. 300621
Identification
Synonyms
EPZ-5676, 1380288-88-9
CAS No.
1380288-87-8
M.F.
C
30
H
42
N
8
O
3
M.W.
562.71
Other CAS No.
1380288-88-9
Technical Data
Purity
≥98% HPLC
Solubility
DMSO, Ethanol
Storage
-20℃
Application
EPZ5676 is a potent and selective inhibitor of DOT1L methyltransferase. It inhibits H3K79 methylation and MLL-fusion target gene expression and displays potent cell killing selective for acute leukemia lines bearing MLL translocations.
Safety Data
Reference
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300621, EPZ5676, ≥98%, 1380288-87-8
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