Obeticholic acid, ≥98%

Catalog No. 807627

Identification

Synonyms	6-Ethylchenodeoxycholic acid, INT-747, 6-ECDCA
CAS No.	459789-99-2
M.F.	C₂₆H₄₄O₄
M.W.	420.63

Technical Data

Appearance	White to off-white powder
Purity	≥98% NMR
Solubility	DMSO, Ethanol
Storage	-20℃
Application	Obeticholic acid is a potent and selective farnesoid X receptor (FXR) agonist with EC50 of 99 nM.

Safety Data

Reference

Ho PP, et al. Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):1600-5. Trivedi PJ, et al. Expert Rev Clin Pharmacol. 2016;9(1):13-26. Dong R, et al. Gastroenterology. 2015 Aug;149(2):508.

Obeticholic acid, ≥98%

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