LANCRIX

Vonoprazan fumarate, ≥99%

Catalog No. 862655

Identification
SynonymsTAK-438, TAK 438
CAS No.1260141-27-2
M.F.

C17H16FN3O2S▪C4H4O4

M.W.461.46
Technical Data
Purity≥99% HPLC
SolubilityDMSO
Storage-20℃
ApplicationVonoprazan fumarate is a novel potassium-competitive acid blocker that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.
Safety Data
Reference

Yoneyama T, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 15;1015-1016:42-9. 
Liu L, et al. J Sep Sci. 2016 Feb 4. 
Matsukawa J, et al. Nihon Yakurigaku Zasshi. 2015 Nov;146(5):275-82. 

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