LANCRIX

Canagliflozin hemihydrate, ≥99%

Catalog No. 158424

Identification
SynonymsTA7284, TA-7284, JNJ28431754, JNJ-28431754
CAS No.928672-86-0
M.F.

2(C24H25FO5S)▪H2O

M.W.907.05
Technical Data
Purity≥99%
SolubilityDMSO
Storage-20℃
ApplicationCanagliflozin hemihydrate is a highly potent and selective SGLT2 inhibitor for hSGLT2 with IC50 of 2.2 nM, exhibits 413-fold selectivity over hSGLT1.
Safety Data
Reference

Rodbard HW, et al. Diabetes Obes Metab. 2016 May 10.
Devineni D, et al. Clin Pharmacol Drug Dev. 2015 Jul;4(4):295-304.
Furuhashi M, et al. PLoS One. 2016 Apr 28;11(4):e0154482.

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