LANCRIX

Lonidamine, ≥99%

Catalog No. 544211

Identification
SynonymsDiclondazolic acid
CAS No.50264-69-2
M.F.

C15H10Cl2N2O2

M.W.321.16
EC No.256-510-0
MDL No.MFCD00866285
PubChem Substance ID24278515
Technical Data
AppearanceWhite to off-white powder
Assay≥99% HPLC
SolubilityDMSO, Ethanol
StorageCool & Dry
ApplicationInhibits the energy metabolism of neoplastic cells by interfering with hexokinase and disrupting uncoupler-stimulated mitochondrial electron transport; damages cell and mitochondrial membranes.
Safety Data
SymbolGHS08GHS07
Hazard StatementsH302-H351-H360
Precautionary StatementsP201-P281-P308 + P313
Hazard SymbolsT
Risk StatementsR60-22-40
Safety StatementsS53-22-36/37/39-45
WGK Germany3
RTECSNK7886000
Reference

De Martino, C., et al. 1984. Oncology. 41: 15-29. PMID: 6717891

Gong, X., et al. 2002. Br. J. Pharmacol. 137: 928-936. PMID: 12411425

Del Bufalo, D., et al. 2004. Neoplasia. 6: 513-522. PMID: 15548359

Sánchez, Y., et al. 2010. J. Pharmacol. Exp. Ther. 335: 114-123. PMID: 20605902

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