LANCRIX

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride, ≥99%

Catalog No. 576606

Identification
SynonymsMPTP hydrochloride
CAS No.23007-85-4
M.F.

C12H15N·HCl

M.W.209.72
Beilstein No.3707312
MDL No.MFCD00012790
Technical Data
AppearanceWhite crystal
Melting Point (°C)253-255℃
Purity≥99% HPLC
SolubilityDMSO, Methanol, Water
StorageCool & Dry
ApplicationIt's a neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. It's widely used in research to induce Parkinson′s disease models in primates.
Safety Data
SymbolGHS06
Hazard StatementsH301 + H311 + H331-H315-H319-H335
Precautionary StatementsP261-P280-P301 + P310-P305 + P351 + P338-P311
Hazard SymbolsT
Risk StatementsR25-36/37/38-39/23/24/25
Safety StatementsS26-39-45
UN No.2811
Hazard Class6.1
Packing GroupII
WGK Germany3
RTECSUT8358950
Reference

Burns, R.S., et al.: Proc. Natl. Acad.Sci. USA, 80, 4546 (1983)

Langston, J.W., et al.: Science, 219, 979 (1983)

Mogi, M., et al.: Neurosci. Lett., 250, 25 (1998)

Przedborski, S. and Jackson-Lewis, V., Mov. Disord., 13, 35 (1998)

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Subject 576606, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride, ≥99%, 23007-85-4
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