Diltiazem hydrochloride, ≥99%

Catalog No. 317052

Identification

Synonyms	(+)-cis-Diltiazem hydrochloride
CAS No.	33286-22-5
M.F.	C₂₂H₂₆N₂O₄S·HCl
M.W.	450.98
Beilstein No.	4228706
EC No.	251-443-3
MDL No.	MFCD00069252
PubChem Substance ID	24277849

Technical Data

Appearance	White Crystalline powder
Melting Point (°C)	210-215℃
Specific Rotation (°)	+110° to +116°
Assay	≥99%
Solubility	DMSO, Methanol, Water
Storage	Room temperature
Application	Diltiazem hydrochloride is a calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).

Safety Data

Symbol	GHS07
Hazard Statements	H302
Hazard Symbols	Xn
Risk Statements	R22
Safety Statements	S36
WGK Germany	3
RTECS	DL0310000

Reference

Sean Ekins et al Drug Metab. Dispos. 38, 2302-8, (2010)
Margot Brickelmaier et al Antimicrob. Agents Chemother. 53, 1840-9, (2009)
Sekiguchi-Tonosaki, M., et al. Am. J. Physiol. Cell Physiol. 296, C1195-206, (2009)
Phedias Diamandis et al Nat. Chem. Biol. 3, 268-73, (2007)
Dobrev, D., et al. Br. J. Pharmacol. 127, 576, (1999)
Gunthorpe, M.J., et al. J. Physiol. 519, 713, (1999)

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Diltiazem hydrochloride, ≥99%

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