LANCRIX

SAHA, ≥99%

Catalog No. 844075

Identification
SynonymsSuberoylanilide hydroxamic acid, Vorinostat
CAS No.149647-78-9
M.F.

C14H20N2O3

M.W.264.32
MDL No.MFCD00945317
Technical Data
AppearanceWhite or off-white powder
Assay≥99%
SolubilityDMSO, Methanol
Storage-20℃
ApplicationSAHA is a potent, reversible pan-histone deacetylase (HDAC) inhibitor. It inhibits both class I and class II HDACs, altering gene transcription and inducing cell cycle arrest and/or apoptosis in a wide variety of transformed cells.
Safety Data
SymbolGHS08
Hazard StatementsH341-H360
Precautionary StatementsP201-P281-P308 + P313
Hazard SymbolsT
Risk StatementsR61-68
Safety StatementsS53-36/37-45
WGK Germany3
Reference

Munster P.N., et al. Br. J. Cancer 104, 1828-1835, (2011)
Shankar S., et al. Mol. Cancer Ther. 8, 1596-1605, (2009)
Deroanne, C.F., et al.: Oncogene, 21, 247 (2002)
Munster P.N., et al. Cancer Res. 61, 8492-8497, (2001)
Richon, V.M., et al. Proc. Natl. Acad. Sci. U. S. A. 95, 3003, (1998)
Richon, V.M., et al. Proc. Natl. Acad. Sci. U. S. A. 93, 5705, (1996)

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