LANCRIX

Procaine, ≥98.5%

Catalog No. 510327

Identification
CAS No.59-46-1
M.F.

C13H20N2O2

M.W.236.31
Beilstein No.0913480
EC No.200-426-9
MDL No.MFCD00007893
Technical Data
AppearanceOff-white crystalline powder
Purity≥98.5%
StorageCool & Dry
ApplicationProcaine is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demetylation and reactivation of methylation-silenced genes such as RARβ and GSTP1.
Safety Data
Reference

Werdehausen, R., et al. 2009. Br J Anaesth. 103: 711-718.
Gao, Z., et al. 2009. Oncol. Rep. 22: 1479-1484.
Endo, M. 2009. Physiol. Rev. 89: 1153-1176.
Wang, H., et al. 2010. Eur. J. Pharmacol. 630: 29-33.
Gal, R. and Libersat, F. 2010. PLoS ONE. 5: e10019.

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