| Appearance | Deep blue purple crystalline powder |
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| Purity | ≥99% HPLC |
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| Assay | ≥970 μg/mg |
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| Solubility | Soluble in water (0.5 mg/ml), 100% ethanol (warm) (1 mg/ml), DMSO (15 mg/ml), and methanol. |
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| Storage | 2-8℃, protected from light |
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| Application | Mitomycin C is part of a family of azidine natural products. It is a DNA crosslinking and damaging agent making it useful as an antibiotic antitumor product. When crosslinking, Mitomycin C displays absolute specificity and high efficiency for the CpG sequence. Mammalian Cells treated with Mitomycin C (0.4 mg/mL for 5 min) can undergo apoptosis through upregulation of Bad, Fas, FasL and phosphorylated p53 along with activation of caspase-3, caspase-8, and caspase-9 activating both the intrinsic a |
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