LANCRIX

GDC-0941, ≥98%

Catalog No. 782306

Identification
SynonymsGDC0941
CAS No.957054-30-7
M.F.

C23H27N7O3S2

M.W.513.64
Technical Data
AppearanceWhite crystal
Purity≥98% HPLC
SolubilityDMSO
Storage-20℃
ApplicationGDC-0941 is a potent inhibitor of PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ. GDC-0941 demonstrated broad spectrum of activity in breast, ovarian, lung, and prostate cancer models. Studies has also shown GDC-0941 may enhance anti-tumor activity of Docetaxel in human breast cancer models.
Safety Data
Reference

Bharill P, et al. Front Genet. 4:34, (2013)
Zou ZQ, et al. Mol Med Rep. 5(2):503-8, (2012)
Wallin JJ, et al. Clin Cancer Res. 18(14):3901-11, (2012)
Wullschleger S, et al. Anticancer Res. ;32(2):415-20, (2012)
Burrows N, et al. J Clin Endocrinol Metab. 96(12):E1934-43, (2011)

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