CI994, ≥99%

Catalog No. 737363

Identification

Synonyms	Acetyldinaline, Tacedinaline
CAS No.	112522-64-2
M.F.	C₁₅H₁₅N₃O₂
M.W.	269.30
MDL No.	MFCD00866266

Technical Data

Appearance	White powder
Assay	≥99% HPLC
Solubility	DMSO
Storage	-20℃
Application	CI994 is an oral cytostatic drug with impressive differential activity against leukemic cells & normal stem-cells. It is used for combination therapy for selected tumors including non-small cell lung, pancreatic, breast, and colorectal cancers. It acts as a histone deacetylase inhibitor.

Safety Data

Symbol	GHS07
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Hazard Symbols	Xi
Risk Statements	R36
Safety Statements	S26
WGK Germany	3
RTECS	CU8702023

Reference

Pontiki, E. et al. Med, Res. Rev., 32, 1, (2012) Gediya, L.K., et al. Bioorg. Med. Chem. 16, 3352-3360, (2008) Hubeek, I., et al. Oncol. Rep. 19, 1517-1523, (2008) Pauer, L.R. et al. Cancer Invest., 22, 886, (2004) Nemunaitis, J.J. et al. Cancer J., 9, 58. (2003)

CI994, ≥99%

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