LANCRIX

Ivacaftor, ≥98%

Catalog No. 564586

Identification
SynonymsVX 770, Kalydeco
CAS No.873054-44-5
M.F.

C24H28N2O3

M.W.392.49
Technical Data
AppearanceOff-white crystalline powder
Assay≥98% HPLC
SolubilityDMSO
Storage-20℃
ApplicationIvacaftor is a potentiator approved for patients with the G551D mutation of cystic fibrosis.
Safety Data
Reference

Vachel L, et al. J Cyst Fibros. 2013; pii: S1569-1993(13)00084-2.
Yu H, et al. J Cyst Fibros. 2012;11(3):237-45
Yarlagadda S, et al. Am J Respir Crit Care Med 2012;186(7), 694-696
Flume PA, et al. Chest. 2012;142(3):718-24
Pettit RS, et al. Ann Pharmacother. 2012;46(7-8):1065-75
Eckford PD, et al. J Biol Chem. 2012;287(44):36639-49

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