LANCRIX

Anagrelide hydrochloride, ≥99%

Catalog No. 735554

Identification
SynonymsBL 4162A
CAS No.58579-51-4
M.F.

C10H7Cl2N3O·HCl

M.W.292.55
Technical Data
AppearanceWhite or off-white powder
Melting Point (°C)＞300℃
Purity≥99% HPLC
SolubilityDMSO
Storage2-8℃
ApplicationAnagrelide hydrochloride is a potent type III phosphodiesterase (PDE3) inhibitor. IC50 = 36 nM. It inhibits platelet aggregation and produces potent thrombocytopenic effects via inhibition of megakaryocyte maturation.
Safety Data
Reference

Penka M, et al. Vnitr Lek. 2013 Jun;59(6):516-31
Okamoto S, et al. Int J Hematol. 2013 Mar;97(3):360-8
Wang G, et al. Br J Pharmacol. 2005 Oct;146(3):324-32
Mazur EM, et al. Blood. 1992 Apr 15;79(8):1931-7
Gillespie E., et al. Biochem Pharmacol. 1988 Jul 15;37(14):2866-8

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Subject 735554, Anagrelide hydrochloride, ≥99%, 58579-51-4
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