LANCRIX

PCI-24781, ≥98%

Catalog No. 821737

Identification
SynonymsCRA-024781
CAS No.783355-60-2
M.F.

C21H23N3O5

M.W.397.42
Technical Data
AppearanceOff-white powder
Assay≥98%
SolubilityDMSO
Storage-20℃
ApplicationA novel broad spectrum HDAC inhibitor targeting HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10. A Phase I study of PCI-24781 in subjects with lymphoma is currently ongoing.
Safety Data
Reference

Park JM, et al. PLoS One. 2013 May 28;8(5):e65369
Kitamura T, et al. J Hepatol. 2012 Jul;57(1):84-91
Bantscheff M, et al. Nat Biotechnol. 2011 Mar;29(3):255-65
Yang C, et al. Anticancer Res. 2011 Apr;31(4):1115-23
Singh MM, et al. Neuro Oncol. 2011 Aug;13(8):894-903
Yang C, et al. Cancer Chemother Pharmacol. 2011 Feb;67(2):439-46

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