LANCRIX

TG101209, ≥99%

Catalog No. 768357

Identification
CAS No.936091-14-4
M.F.

C26H35N7O2S

M.W.509.67
Technical Data
AppearanceWhite powder
Assay≥99%
SolubilityDMSO
Storage-20℃
ApplicationTG101209 is a selective JAK2 inhibitor, less potent to Flt3 and RET, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations.
Safety Data
Reference

Ansbro MR, et al. PLoS One. 2013 Apr 10;8(4):e60334
Sun Y, et al. J Thorac Oncol. 2011 Apr;6(4):699-706
Ramakrishnan V, et al. Am J Hematol. 2010 Sep;85(9):675-86
Wang Y, et al. Blood. 2009 Dec 3;114(24):5024-33

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