LANCRIX

GSK690693, ≥98%

Catalog No. 318741

Identification
CAS No.937174-76-0
M.F.

C21H27N7O3

M.W.425.48
Technical Data
AppearanceOff-white powder
Assay≥98%
SolubilityDMSO
Storage-20℃
ApplicationGSK690693 is a pan-Akt inhibitor targeting Akt1/2/3. It also exhibits some inhibition for AMPK, PKA and PAK and PKC isoforms. It displays antiproliferative and apoptotic effects in tumor cell lines.
Safety Data
Reference

Podolski-Renić A, et al. Cancer Chemother Pharmacol. 2013 Sep;72(3):683-97
Makhov PB, et al. Mol Cancer Ther. 2012 Jul;11(7):1510-7
Guo JP, et al. J Biol Chem. 2011 Oct 28;286(43):37389-98
Carol H, et al. Pediatr Blood Cancer. 2010 Dec 15;55(7):1329-37

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