AZD5438, ≥98%

Catalog No. 873180

Identification

CAS No.	602306-29-6
M.F.	C₁₈H₂₁N₅O₂S
M.W.	371.46

Technical Data

Appearance	Off-white solid
Assay	≥98%
Solubility	DMSO
Storage	-20℃
Application	AZD5438 is a potent inhibitor of CDK1/2/9. It is less potent to CDK5/6 and also inhibits GSK3β. It exhibits antiproliferative activity in human tumor cell lines.

Safety Data

Reference

Nagaria TS, et al. Neoplasia. 2013 Aug;15(8):939-51 Raghavan P, et al. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):e507-14 Boss DS, et al. Ann Oncol. 2010 Apr;21(4):884-94 Byth KF, et al. Mol Cancer Ther. 2009 Jul;8(7):1856-66

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