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Ivabradine hydrochloride, ≥99%

Catalog No. 273321

Identification
CAS No.148849-67-6
M.F.

C27H36N2O5·HCl

M.W.505.05
MDL No.MFCD00929899
Technical Data
AppearanceWhite powder
Assay≥99% HPLC
SolubilityDMSO, Methanol
Storage2-8℃
ApplicationIvabradine hydrochloride is an open channel blocker of neuronal I(h) and related cardiac I(f) channels. It has antianginal activity. It lowers heart rate and reduces myocardial oxygen demand.
Safety Data
SymbolGHS09
Hazard StatementsH400
Precautionary StatementsP273
Hazard SymbolsN
Risk StatementsR50/53
Safety StatementsS60-61
WGK Germany3
Reference

Lodhi M, et al. Int J Pharm Investig. 3(1):47-53, (2013)
Fang, Y., et al. J. Cardiovasc. Pharmacol. 59, 260-267, (2012)
Kroller-Schon, S., et al. Basic Res. Cardiol. 106, 1147-1158, (2011)
DiFrancesco, D., et al. Drugs, 64, 1757 (2004)
Borer, J.S., et al. Circulation, 107, 817 (2003)

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