Azithromycin dihydrate, 945-1030 ug/mg

Catalog No. 373874

Identification

CAS No.	117772-70-0
M.F.	C₃₈H₇₂N₂O₁₂·2H₂O
M.W.	785.02
MDL No.	MFCD01862248

Technical Data

Appearance	White crystalline powder
Specific Rotation (°)	-45° to -49°
Assay	945-1030 ug/mg (as dry basis)
Solubility	Chloroform, Ethanol
Storage	Protected from light
Application	Azithromycin dihydrate is a macrolide antibiotic, azalide subclass. It binds to the 50S subunit of the 70S bacterial ribosomes and inhibits RNA-dependent protein synthesis in bacterial cells. Azithromycin also has anti-immunomodulatory/anti-inflammatory properties, which make it useful in treating cystic fibrosis.

Safety Data

WGK Germany	3
RTECS	RN6960000

Reference

West SK, et al. PLoS Negl Trop Dis. 7(8):e2415, (2013) Togami K, et al. Biol Pharm Bull. 36(9):1494-9, (2013) Yamauchi K., et al. Int. J. Biochem. Cell Biol. 5, 667-678, (2009) Elizur A., et al. Chest 133, 489-495, (2008) Langtry, H.D., et al.: Drugs, 56, 273 (1998)

Azithromycin dihydrate, 945-1030 ug/mg

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