LANCRIX

BMS-708163, ≥98%

Catalog No. 735523

Identification
SynonymsAvagacestat
CAS No.1146699-66-2
M.F.

C20H17ClF4N4O4S

M.W.520.88
Technical Data
AppearanceWhite powder
Assay≥98%
SolubilityDMSO
Storage-20℃
ApplicationBMS-708163 is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42, demonstrating a 193-fold selectivity against Notch.
Safety Data
Reference

Dockens R, et al. Clin Pharmacokinet. 2012 Oct 1;51(10):681-93
Tong G, et al. Clin Drug Investig. 2012 Nov;32(11):761-9
Tong G, et al. Clin Ther. 2012 Mar;34(3):654-67
Gu H, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 1;878(25):2319-26

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