LANCRIX

BMS-536924, ≥98%

Catalog No. 231425

Identification
CAS No.468740-43-4
M.F.

C25H26ClN5O3

M.W.479.96
Technical Data
Assay≥98%
SolubilityDMSO >90 mg/ml (25℃)
Storage-20℃
ApplicationBMS-536924 is an ATP-competitive IGF-1R/IR inhibitor, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
Safety Data
Reference

Chang AY, et al. Anticancer Drugs. 2013 Mar;24(3):251-9
Kang HJ, et al. Cell Death Dis 2012;3, e336
Breinig M, et al. Clin Cancer Res 2011;17(8), 2237-2249
Dool CJ, et al. Endocr Relat Cancer. 2011 Nov 14;18(6):699-709

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