AT 101, ≥98%

Catalog No. 558306

Identification

Synonyms	(R)-(-)-Gossypol
CAS No.	90141-22-3
M.F.	C₃₀H₃₀O₈
M.W.	518.56

Technical Data

Assay	≥98%
Solubility	DMSO >80 mg/ml; Ethanol >80 mg/ml
Storage	-20℃
Application	AT101, the R-(-) enantiomer of Gossypol, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID.

Safety Data

Reference

Lane R. et al. Lancet. 2013 Aug 31;382(9894):762 Karaca B, et al. Mol Biol Rep. 2013 Jun;40(6):3925-33 Liu G, et al. Clin Cancer Res. 2009 May 1;15(9):3172-6 Balakrishnan K, et al. Blood. 2009 Jan 1;113(1):149-53

Availability: Ships in 4 days

For research use only.

Inquire

	(*Required Field)
*Name
*Organization Name
*Country
*Email Address
Phone
Subject	558306, AT 101, ≥98%, 90141-22-3
*Message
*Code