Lubiprostone, ≥99%

Catalog No. 183573

Identification

Synonyms	(11α)-16,16-Difluoro-11-hydroxy-9,15-dioxo-prostan-1-oic Acid; Ru 0211
CAS No.	136790-76-6
M.F.	C₂₀H₃₂F₂O₅
M.W.	390.46

Technical Data

Appearance	White crystal or crystalline powder
Purity	≥99% HPLC
Solubility	Chloroform
Storage	-20℃
Application	Lubiprostone is a bicyclic fatty acid metabolite analog of Prostaglandin E1. It activates specific chloride channels in the gastrointestinal tract to stimulate intestinal fluid secretion, increase gastrointestinal transit, and improve symptoms of constipation.

Safety Data

Reference

Farthing, M., et al.: Drugs, 56, 11 (1998) Pare, P., et al.: Am. J. Gastroenterol., 96, 3130 (2001) Sloots, C., et al.: Aliment. Pharmacol. Ther., 16, 759 (2002) Coremans, G., et al.: Digestion, 67, 82 (2003)

Lubiprostone, ≥99%

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