LANCRIX

Regorafenib, ≥98%

Catalog No. 460712

Identification
SynonymsBAY 73-4506
CAS No.755037-03-7
M.F.

C21H15ClF4N4O3

M.W.482.82
Technical Data
Assay≥98%
SolubilityDMSO >90 mg/ml (25℃)
Storage-20℃
ApplicationRegorafenib is an oral multi-kinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinase. Regorafenib shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition.
Safety Data
Reference

Cyran CC, et al. PLoS One. 2013 Sep 30;8(9):e76009
André T, et al. Bull Cancer. 2013 Oct 1;100(10):1027-1029
Adenis A, et al. Acta Oncol. 2013 Nov;52(8):1789-90
Wilhelm SM, et al. Int J Cancer. 2011 Jul 1;129(1):245-55

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