LANCRIX

Dacomitinib, ≥98%

Catalog No. 717371

Identification
SynonymsPF-00299804
CAS No.1110813-31-4
M.F.

C24H25ClFN5O2

M.W.469.94
Technical Data
Assay≥98%
SolubilityDMSO >10 mg/ml (25℃)
Storage-20℃
ApplicationDacomitinib is an orally bioavailable and highly selective inhibitor of the pan-epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity.
Safety Data
Reference

Bello CL, et al. Cancer Chemother Pharmacol. 2013 Aug;72(2):379-85
Ramalingam SS, et al. J Clin Oncol. 2012 Sep 20;30(27):3337-44
Kalous O, et al. Mol Cancer Ther. 2012 Sep;11(9):1978-87
Ather F, et al. PLoS One. 2013;8(2):e56112

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