LANCRIX

Ascomycin, ≥98.5%

Catalog No. 247855

Identification
SynonymsImmunomycin, FK520, Analog of FK-506, FR-900520, L-683590, NSC 106410, WS 7238A
CAS No.11011-38-4
M.F.

C43H69NO12

M.W.792.01
MDL No.MFCD06198665
Technical Data
AppearanceWhite to off-white solid.
Purity≥98.5% HPLC
SolubilityDMSO, Ethanol
Storage-20℃
ApplicationAscomycin is an ethyl analog of FK506 with similar immunosuppressant properties. It acts by binding to immunophilins. It Inhibits the synthesis of Th-1 and Th-2 type cytokines in target cells.
Safety Data
Reference

Bulusu MA, et al. Prog Chem Org Nat Prod. 2011;94:59-126
Sierra-Paredes G, et al. CNS Neurosci Ther. 2008 Spring;14(1):36-46
Revill WP, et al. J Pharmacol Exp Ther. 2002 Sep;302(3):1278-85
Van Leent EJ, et al. Arch Dermatol. 1998 Jul;134(7):805-9
ARAI T,  et al. J Antibiot (Tokyo). 1962 Nov;15:231-2

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