LANCRIX

Cyclosporin A, ≥98%

Catalog No. 181102

Identification
SynonymsCsA, Ciclosporin A, Cyclosporine
CAS No.59865-13-3
M.F.

C62H111N11O12

M.W.1202.61
Beilstein No.3647785
MDL No.MFCD00274558
Technical Data
Assay≥98% HPLC
SolubilityDMSO, Ethanol
Storage-20℃
ApplicationCyclosporin A is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. It inhibits phosphatase activity of calcineurin. It also inhibits formation and opening of the mitochondrial permeability transition pore (MPTP).
Safety Data
Reference

Kraeuter M, et al. Drug Des Devel Ther. 2013 Nov 28;7:1421-6
Guaguère E, et al. Vet Dermatol. 2004 Apr;15(2):61-74
Ho S, et al. Clin Immunol Immunopathol. 1996 Sep;80(3 Pt 2):S40-5
Liu J, et al. Cell. 1991 Aug 23;66(4):807-15

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