LANCRIX

Cyclosporin H, ≥95%

Catalog No. 217200

Identification
SynonymsCyclosporine H, Sandoz 37-839
CAS No.83602-39-5
M.F.

C62H111N11O12

M.W.1202.63
Technical Data
AppearanceWhite powder
Purity≥95% HPLC
SolubilityEthanol, Acetone, Ethyl acetate, and Chloroform
Storage-20℃
ApplicationCyclosporin H is immunologically inactive. It is a potent inhibitor of tumor promoting phorbol ester TPA/PMA in mouse skin in vivo. It is a potent inhibitor of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro. It is also a potent and selective antagonist of formyl peptide receptor.
Safety Data
Reference

Stenfeldt AL, et al. Inflammation. 2007 Dec;30(6):224-9
Potter B, et al. Org Biomol Chem. 2003 May 7;1(9):1466-74
de Paulis A, et al. J Allergy Clin Immunol. 1996 Jul;98(1):152-64
Wenzel-Seifert K, et al. J Immunol. 1993 May 15;150(10):4591-9
Bavandi A, et al. Exp Dermatol. 1992 Nov;1(4):199-205

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