LANCRIX

Dasatinib monohydrate, ≥99%

Catalog No. 414770

Identification
CAS No.863127-77-9
M.F.

C22H26ClN7O2S·H2O

M.W.506.02
MDL No.MFCD08704581
Technical Data
AppearanceWhite or almost white powder
Assay≥99% HPLC
SolubilitySlightly soluble in ethanol and methanol
StorageRoom temperature
ApplicationDasatinib is a 2-aminothiazole-derived inhibitor of SRC family kinases. Dasatinib inhibits c-Abl and Bcr-Abl tyrosine kinase activity and shows efficacy against imatinib-resistant Bcr-Abl mutations.
Safety Data
SymbolGHS08GHS07
Hazard StatementsH302-H360-H373
Precautionary StatementsP260-P281-P301+P310-P321-P405-P501A
Hazard SymbolsTXn
Risk StatementsR22-48/22-61
Safety StatementsS53-20-36-45-60
Reference

Doggrell, S.A. 2005. Expert Opin Investig Drugs. 14: 89-91. PMID: 15709925
Das, J., et al. 2006. J. Med. Chem. 49: 6819-6832. PMID: 17154512
Talpaz, M., et al. 2006. N. Engl. J. Med. 354: 2531-2541. PMID: 16775234

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