25-Hydroxyvitamin D2, ≥98%

Catalog No. 878503

General Information

Synonyms	Ercalcidiol, 25-Hydroxyergocalciferol, 25-Hydroxycalciferol
CAS No.	21343-40-8
M.F.	C₂₈H₄₄O₂
M.W.	412.65
Beilstein No.	4716773
MDL No.	MFCD02683431

Technical Data

Appearance	White to off-white solid
Purity	≥98% HPLC
Solubility	Soluble to 10 mM in DMSO and to 10 mM in ethanol
Storage	-20℃, under inert atmosphere, protected from light.
Description	Vitamin D aids in the absorption of calcium and has central roles in bone formation and maintenance, hypertension, cancer, and immunity. Vitamin D2 is produced in fungi, including yeast, from ergosterol in response to ultraviolet radiation. 25-hydroxy Vitamin D2 is an intermediate produced from vitamin D2 by cytochrome P450 isoforms in vertebrates. It is subsequently metabolized to 1,25-dihydroxy vitamin D2, which is an agonist for the vitamin D receptor.
Biochem/physiol Actions	Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.

Safety Data

Symbol	GHS08 GHS06
Hazard Statements	H300 +H310 + H330-H372
Precautionary Statements	P260-P264-P280-P284-P301 + P310-P302 + P350
Hazard Symbols	T+
Risk Statements	R24/25-26-48/25
Safety Statements	S28-36/37-45
UN No.	2811
Hazard Class	6.1
Packing Group	II
WGK Germany	3

Reference

Jones et al (1976) An in vitro study of vitamin D₂ hydroxylases in the chick. J.Biol.Chem. 251 24. PMID: 1081537.

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25-Hydroxyvitamin D2, ≥98%

Size	Price	Quantity	Favorites
1 mg	USD110
10 mg	USD550

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