AT 101, ≥98%

Catalog No. 558306

General Information

Synonyms	(R)-(-)-Gossypol
CAS No.	90141-22-3
M.F.	C₃₀H₃₀O₈
M.W.	518.56

Technical Data

Assay	≥98%
Solubility	DMSO >80 mg/ml; Ethanol >80 mg/ml
Storage	-20℃
Description	AT101, the R-(-) enantiomer of Gossypol, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID.

Reference

Lane R. et al. Lancet. 2013 Aug 31;382(9894):762
Karaca B, et al. Mol Biol Rep. 2013 Jun;40(6):3925-33
Liu G, et al. Clin Cancer Res. 2009 May 1;15(9):3172-6
Balakrishnan K, et al. Blood. 2009 Jan 1;113(1):149-53

Size	Price	Quantity	Favorites
20 mg	USD244
50 mg	USD488
100 mg	USD792

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For research use only. Not for human use.

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AT 101, ≥98%

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