Amlodipine, ≥99%

Catalog No. 022763

General Information

Synonyms	(R,S)-Amlodipine; Amlopres; Intervask; Pelmec; UK-48340
CAS No.	88150-42-9
M.F.	C₂₀H₂₅ClN₂O₅
M.W.	408.88
EC No.	425-820-1
MDL No.	MFCD00887594

Technical Data

Appearance	White or off-white powder
Assay	≥99%
Solubility	Acetone, Chloroform, Ethyl Acetate, Methanol
Storage	2-8℃
Description	A dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.

Safety Data

Symbol	GHS09 GHS08 GHS06 GHS05
Hazard Statements	H301-H318-H373-H410
Precautionary Statements	P260-P301+P310-P305+P351+P338-P321-P405-P501
Hazard Symbols	T N
Risk Statements	R25-41-48/22-50/53
Safety Statements	S26-36/37/39-45-60-61
UN No.	UN2811
Hazard Class	6.1
Packing Group	III

Reference

Ueda, S., et al. 1993. Br. J. Clin. Pharmacol. 36: 561-566. PMID: 12959273
Mason, R.P., et al. 2003. Arterioscler Thromb. Vasc. Biol. 23: 2155-2163. PMID: 14512371
Asano, Y., et al. 2003. Biochem. Biophys. Res. Commun. 311: 625-628. PMID: 14623316
Yoshida, J., et al. 2003. Eur. J. Pharmacol. 472: 23-31. PMID: 12860469
Yu, T., et al. 2003. Hypertension. 42: 329-334. PMID: 12900427
Zhou, M.S., et al. 2004. Am. J. Hypertens. 17: 167-171. PMID: 14751660