Olaparib, ≥98%

Catalog No. 744876

General Information

Synonyms	KU 0059436, AZD 2281
CAS No.	763113-22-0
M.F.	C₂₄H₂₃FN₄O₃
M.W.	434.46

Technical Data

Appearance	White powder
Purity	≥98%
Solubility	DMSO, Methanol
Storage	2-8℃
Description	A potent poly(ADP-ribose) polymerase (PARP) inhibitor shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.

Reference

Weston, V.J. et al.: Blood, 116, 4578 (2010)
Senra, J.M. et al.: Mol. Cancer Therap., 10, 1949 (2011)
Schaefer, N.G. et al.: Nuc. Med. Comm., 32, 1046 (2011)

Size	Price	Quantity	Favorites
50 mg	USD56
500 mg	USD364

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

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Olaparib, ≥98%

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