Adefovir dipivoxil, ≥99.5%

Catalog No. 205537

General Information

CAS No.	142340-99-6
M.F.	C₂₀H₃₂N₅O₈P
M.W.	501.47
MDL No.	MFCD00869897

Technical Data

Appearance	White or off-white powder
Melting Point (°C)	98-102℃
Assay	≥99.5%
Solubility	DMSO
Storage	-20℃
Description	Adefovir is an antiviral acyclic nucleoside phosphonate (ANP) analog. Adefovir is used to treat hepatitis B infections. It is used to study organ-specific toxicity and immune mechanisms of Adefovir treatment.

Safety Data

Symbol	GHS07
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Hazard Symbols	Xn
Risk Statements	R20/21/22
Safety Statements	S36/37
WGK Germany	3

Reference

Ming, X., et al. Biochem. Pharmacol., 79, 455 (2010)
Fourches, D., et al. Chem. Res. Toxicol., 23, 171 (2010)
Fliri, A., et al. J. Med. Chem., 52, 8038 (2009)
Helen Cooksley, et.al Antimicrob. Agents Chemother. 52, 312-320, (2008)
Marcellin P, et. Al N. Engl. J. Med. 348, 808-816, (2003)
Julien Delmas, et. Al Antimicrob. Agents Chemother. 46, 425-433, (2002)
Ho ES, et. Al J. Am. Soc. Nephrol. 11, 383-393, (2000)