Nafamostat mesylate, ≥98%

Catalog No. 327207

General Information

Synonyms	FUT-175
CAS No.	82956-11-4
M.F.	C₁₉H₁₇N₅O₂ · 2CH₄O₃S
M.W.	539.58
MDL No.	MFCD00941430

Technical Data

Appearance	White powder
Melting Point (°C)	256-260℃
Assay	≥98%
Solubility	Soluble in DMSO and Water
Storage	2-8℃
Description	Nafamostat mesylate is a non-peptide proteaseinhibitor.

Safety Data

Symbol	GHS08
Hazard Statements	H361
Precautionary Statements	P280 - P308+313
Hazard Symbols	Xn
Risk Statements	R62, R63
Safety Statements	S36/37/39, S45
RTECS	DG2736000

Reference

Mori et al (2003) Nafamostat mesilate is an extremely potent inhibitor of human tryptase. J.Pharmacol.Sci. 92 420. PMID: 12939527.

Sendo et al (2003) A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary dysfunction induced in rats by a radiographic contrast medium. Br.J.Pharmacol. 138 959. PMID: 12642398.

Chen et al (2006) Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. J.Allergy Clin.Immunol. 118 105. PMID: 16815145.