Ramelteon, ≥99%

Catalog No. 255017

General Information

Synonyms	Rozerem, TAK-375
CAS No.	196597-26-9
M.F.	C₁₆H₂₁NO₂
M.W.	259.34

Technical Data

Appearance	White to off-white powder
Melting Point (°C)	112-116℃
Specific Rotation (°)	-55° to -60°
Assay	≥99% HPLC
Solubility	DMSO, Ethanol
Storage	-20℃
Description	Ramelteon is a melatonin receptor agonist with both high affinity for melatonin MT1 and MT2 receptors and selectivity over the MT3 receptor. Ramelteon demonstrates full agonist activity in vitro in cells expressing human MT1 or MT2 receptors, and high selectivity for human MT1 and MT2 receptors compared to the MT3 receptor.

Reference

Norris ER, et al. J Affect Disord. 2013 Jan 10;144(1-2):141-7
Liu J, et al. Int J Clin Pract. 2012 Sep;66(9):867-73
Mets MA, et al. Sleep. 2011 Oct 1;34(10):1327-34
Borja NL, et al. Clin Ther. 2006 Oct;28(10):1540-55

Size	Price	Quantity	Favorites
5 mg	USD75
10 mg	USD135
25 mg	USD270

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For research use only. Not for human use.

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Ramelteon, ≥99%

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