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Temozolomide, ≥99%

Catalog No. 488316

General Information
SynonymsMethazolastone; NSC 362856; Sch 52365; Temodal; Temodar
CAS No.85622-93-1


MDL No.MFCD00866492
Technical Data
AppearanceWhite or light pink powder
Assay≥99% HPLC
SolubilitySoluble in DMSO, Acetone and Methanol
DescriptionTemozolomide is an imidazotetrazine alkylating agent. An antineoplastic.
Safety Data
Hazard StatementsH302-H315-H319-H335-H350-H360
Precautionary StatementsP201-P261-P305 + P351 + P338-P308 + P313
Hazard SymbolsT
Risk StatementsR45-46-60-61-22-36/37/38
Safety StatementsS53-26-36/37-45
WGK Germany3

Plowman et al (1994) Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res. 54 3793. PMID: 8033099.

Clark et al (1995) Antitumor imidazotetraazines. 32. Synthesis of novel imidazotetrazinones and related bicyclic heterocycles to probe the mode of action of the antitumor drug temozolomide. J.Med.Chem. 38 1493. PMID: 7739008.

Bodell et al (2003) Formation of DNA adducts and induction of lacI mutations in big blue rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric tumors. Cancer Epidemiol.Biomarkers Prevent. 12 545.

Kanzawa et al (2004) Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ. 11 448. PMID: 14713959.

Size Price Quantity Favorites
100 mg USD36
1 g USD180
5 g USD320

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

> Certificate of Analysis