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AICAR, ≥98%

Catalog No. 707041

General Information
SynonymsArasine; GP 1-110; NSC 105823
CAS No.2627-69-2
M.F.

C9H14N4O5

M.W.258.23
EC No.220-097-5
MDL No.MFCD00869751
PubChem Substance ID24724407
Technical Data
AppearanceWhite crystalline powder
Purity≥98% HPLC
SolubilitySoluble in DMSO, Methanol and Water
Storage-20℃
DescriptionAICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
Safety Data
SymbolGHS07
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Hazard SymbolsXi
Risk StatementsR36/37/38
Safety StatementsS26-36
WGK Germany3
Reference

Giri et al (2004) 5-Aminoimidazole-4-carboxamide-1-β-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. J.Neurosci. 24 479. PMID: 14724246.

Ayasolla et al (2005) 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Aβ peptide-induced inflammatory mediators in astroglia. J.Neuroinflammation 2 21. PMID: 16174294.

Kanazawa et al (2007) Adiponectin and AMP kinase activator stimulate proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells. BMC Cell Biol. 8 51. PMID: 18047638.

Giri et al (2008) The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: Implication for Krabbe disease. J.Neurochem. 105 1820. PMID: 18248608.

Size Price Quantity Favorites
1 g USD150
5 g USD565

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

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