Shopping Cart(0) | Register

Email Password 

Remember me on this computer  |  Forgot password?

Luteolin, ≥98%

Catalog No. 622608

General Information
CAS No.491-70-3


Beilstein No.292084
EC No.207-741-0
MDL No.MFCD00017309
PubChem Substance ID24896520
Botanical Source Arachis hypogaea L.
Technical Data
AppearanceYellow green powder
Melting Point (°C)~330°C (lit.)
Assay≥98% HPLC
SolubilitySoluble to 5 mM in 1eq. NaOH and to 50 mM in DMSO
Biological Activity Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation. Also inhibits TNF-α -induced COX-2 expression. Antiproliferative and chemopreventative; inhibits proliferation of Lewis lung carcinoma cells in vivo.
Safety Data
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Hazard SymbolsXi
Risk StatementsR36/37/38
Safety StatementsS26-36
WGK Germany3

Chen et al (2007) Luteolin suppresses inflammation-associated gene expression by blocking NF-κB and AP-1 activation pathway in mouse alveolar macrophage. Life Sci. 81 1602. PMID: 17977562.

Ju et al (2007) A critical role of luteolin-induced reactive oxygen species in blockage of tumour necrosis factor-activated nuclear factor-κB pathway and sensitization of apoptosis in lung cancer cells. Mol.Pharmacol. 71 1381. PMID: 17296806.

Kim et al (2007) Caspase activation and extracellular signal-regulated kinase/Akt inhibition were involved in luteolin-induced apoptosis in Lewis lung carcinoma cells. Ann.N.Y.Acad.Sci. 1090 597.

Kim et al (2011) Luteolin, a novel natural inhibitor of tumor progression locus 2 serine/ threonine kinase, inhibits tumor necrosis factor-α-induced cyclooxygenase-2 expression in JB6 mouse epidermis cells. J.Pharm.Exp.Ther. 338 1013.

Size Price Quantity Favorites
50 mg USD24
100 mg USD40
500 mg USD132

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

> Certificate of Analysis